- Preparation of graphene oxide and graphene platelets and graphene-chitosan composite.
- Design and synthesis of LNA modified molecular beacon oligonucleotide probes (LNA-MB) with attached energy-transfer enhancement moieties for sensitive electrochemical detection of DNA targets (bacterial and/or viral genomes) on a graphene sensor.
- Functionalization of graphene for homogenous covalent grafting of receptor/detector nanostructures (MBs, enzymes).
- Modification of graphene surface/composition by doping methods (N-doping, metals, etc.) for signal enhancement.
- Development of graphene-chitosan composite ink for low-cost fabrication of biosensors using ultrasonic printing of electrical circuits.
- Electrochemical impedance spectroscopy, field-effect transistor and/or cyclic voltammetry for sensitive detection of target analyte on graphene biosensors.
- Development of low-cost polymeric and/or paper supports for fabrication of graphene based electrochemical sensors as part of a lab-on-a-chip system or microfluidic device.
- Design of a diagnostic platform based on developed graphene biosensors.
- Evaluation of clinical performance of developed DNA and glucose biosensors.
The tasks are executed by particular partners of the consortium as 12 interdependent work packages.
No | Work Package Title | Partner | Start Date | End Date |
1 | Preparation of graphene oxide and reduced graphene oxide platelets | 01-01-2013 | 31-12-2015 | |
2 | Design and synthesis of LNA-modified molecular beacon probes | 01-01-2013 | 31-12-2014 | |
3 | Functionalization of graphene with metal nanoparticles and heteroatoms | 01-05-2013 | 31-12-2015 | |
4 | Functionalization of graphene with LNA-modified molecular beacons | 01-07-2013 | 31-12-2015 | |
5 | Development of graphene-chitosan system (ink) for electrical circuit printing | 01-03-2013 | 30-06-2015 | |
6 | Graphene-Based Bio-Field Effect Transistor (Bio-FET) as a Biosensor | 01-04-2013 | 31-12-2015 | |
7 | Electrochemical Biosensor (ECB) - Cyclic Voltammetry CV, Differential Pulse Voltammetry DPV, Square-Wave Voltammetry SWV | 01-07-2013 | 31-12-2015 | |
8 | Graphene-Based Impedimetric Biosensor (BI-Sensor) – Electrochemical Impedance Spectroscopy EIS | 01-03-2013 | 31-12-2015 | |
9 | Synthesis of glucose oxidase-functionalized graphene | 01-10-2013 | 31-12-2015 | |
10 | Development of polymeric and/or paper supports for electrochemical sensors | 01-01-2014 | 31-12-2015 | |
11 | Design of a diagnostic platform based on developed graphene biosensors | 01-01-2014 | 31-12-2015 | |
12 | Evaluation of clinical performance of developed DNA and glucose biosensors | 01-01-2015 | 31-12-2015 |
ZUT/ZN
